We report random lasing in colloidal quantum dots (CQDs) doped disordered polymer. The CdSe/ZnS core-shell CQDs are dispersed in hybrid polymer including two types of monomers with different rates of polymerization. After UV curing, spatially localized random resonators are formed owing to long range refractive-index fluctuations in inhomogeneous polymer with gain. Upon the optical excitation, random lasing action is triggered above the threshold of 7mJ/cm2. Through the investigation on the spectral characteristics of random laser, the wavelengths of random lasers strongly depend on pump position, which confirms that random laser modes originate from spatially localized resnonators. According to power Fourier transform of emission spectrum, the average size of equivalent micro resonators is attributed to be 50 μm. The proposed method provides a facile route to develop random lasers based on CQDs, showing potential applications on random fiber laser and laser displays.