What we have learned about antenatal corticosteroid regimens

Semin Perinatol. 2016 Aug;40(5):291-7. doi: 10.1053/j.semperi.2016.03.005. Epub 2016 Apr 25.

Abstract

Administration of antenatal corticosteroids has been standard of care for women between 24 and 34 weeks of gestation who are at risk for preterm delivery for more than 20 years longer in other parts of the world. Although the benefit of steroids in this population has been confirmed, there remain many questions including the frequency of dosing and whether it is possible to expand the gestational age criteria to women likely to deliver before 24 weeks or after 34 weeks. The MFMU Network has played a major role in answering some of these questions.

Keywords: Antenatal corticosteroids; Betamethasone; Preterm Birth; Respiratory distress.

Publication types

  • Review
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adrenal Cortex Hormones / administration & dosage*
  • Adult
  • Dose-Response Relationship, Drug
  • Evidence-Based Medicine
  • Female
  • Fetal Organ Maturity / drug effects*
  • Gestational Age
  • Humans
  • Infant, Newborn
  • Practice Guidelines as Topic
  • Pregnancy
  • Premature Birth* / prevention & control
  • Randomized Controlled Trials as Topic
  • Respiratory Distress Syndrome, Newborn
  • Treatment Outcome

Substances

  • Adrenal Cortex Hormones

Grants and funding