Continuous positive airway pressure therapy is associated with improvement in overactive bladder symptoms in women with obstructive sleep apnea syndrome

Tumay Ipekci; Gulgun Cetintas; Orcun Celik; Rahmi Gokhan Ekin; Sema Sarac; Ahmet Tunckiran; Yusuf Ozlem Ilbey

doi:10.5173/ceju.2016.674

Continuous positive airway pressure therapy is associated with improvement in overactive bladder symptoms in women with obstructive sleep apnea syndrome

Cent European J Urol. 2016;69(1):78-82. doi: 10.5173/ceju.2016.674. Epub 2016 Jan 18.

Authors

Tumay Ipekci¹, Gulgun Cetintas², Orcun Celik³, Rahmi Gokhan Ekin³, Sema Sarac³, Ahmet Tunckiran¹, Yusuf Ozlem Ilbey³

Affiliations

¹ Baskent University Medical Faculty, Alanya Practise and Research Center, Department of Urology, Antalya, Turkey.
² Sureyyapasa Chest Diseases and Chest Surgery Training and Research Hospital, Department of Chest Diseases, Istanbul, Turkey.
³ Tepecik Teaching and Research Hospital, Department of Urology, Izmir, Turkey.

Abstract

Introduction: To evaluate the impact of continuous positive airway pressure (CPAP) therapy on overactive bladder (OAB) symptoms in women with obstructive sleep apnea syndrome (OSAS).

Material and methods: One-hundred and fifty women underwent an overnight polysomnography study between May 2014 and September 2014. Their voiding symptoms were evaluated using the OAB symptom score (OABSS) and International Consultation on Incontinence Questionnaire Short-Form at OSAS diagnosis and approximately 3-months after CPAP therapy. OSAS severity was assessed according to the apnea-hypopnea-index.

Results: We evaluated 140 women and 111 of them (79.3%) reported symptoms consistent with OAB. There were no statistically significant differences between OSAS severity with a prevalence of OAB (p = 0.92). The prevalence of urinary incontinence (UI) was 35.7% (n = 50) and 39.6% (n = 44) in all patients and patients with OAB, respectively. There were no statistically significant differences between UI with OAB (p = 0.58). Baseline OABSS is comparable between OSAS severity (p = 0.143). After 3-months CPAP therapy, OABSS and ICIQ-SF sum scores were significantly decreased in patients with severe and moderate OSAS (p <0.01), however, change of OABSS sum score was insignificant in patients with mild OSAS (p = 0.44).

Conclusions: CPAP therapy improves the OAB, OABSS and ICIQ-SF scores in women with severe and moderate OSAS. OSAS-induced OAB may be alleviated following CPAP therapy.

Keywords: continuous positive airway pressure; obstructive sleep apnea syndrome; overactive bladder.