Quick reference guide to the new oral anticoagulants

J Vasc Surg. 2016 Jun;63(6):1653-7. doi: 10.1016/j.jvs.2016.02.054. Epub 2016 Apr 21.

Abstract

After the commissioning of new oral anticoagulants for the treatment and prevention of thrombosis, these medications are now widely used within clinical settings. Increasing numbers of patients present to the health services on anticoagulant medications, and it is therefore imperative for surgeons to be aware of the new therapeutic treatments available and how patients will benefit from such interventions. This review highlights the most pertinent learning points for surgeons regarding the indications, pharmacokinetics, and perioperative management of these new oral medications, as a quick reference guide.

Publication types

  • Review

MeSH terms

  • Administration, Oral
  • Anticoagulants / administration & dosage*
  • Anticoagulants / adverse effects
  • Anticoagulants / pharmacokinetics
  • Blood Coagulation / drug effects*
  • Blood Coagulation Tests
  • Drug Monitoring / methods
  • Drug Substitution
  • Fibrinolytic Agents / administration & dosage*
  • Fibrinolytic Agents / adverse effects
  • Fibrinolytic Agents / pharmacokinetics
  • Hemorrhage / chemically induced
  • Humans
  • Patient Selection
  • Risk Assessment
  • Risk Factors
  • Stroke / blood
  • Stroke / etiology
  • Stroke / prevention & control*
  • Thrombosis / blood
  • Thrombosis / etiology
  • Thrombosis / prevention & control*
  • Treatment Outcome

Substances

  • Anticoagulants
  • Fibrinolytic Agents