Base-Metal-Catalyzed Regiodivergent Alkene Hydrosilylations

Xiaoyong Du; Yanlu Zhang; Dongjie Peng; Zheng Huang

doi:10.1002/anie.201601197

Base-Metal-Catalyzed Regiodivergent Alkene Hydrosilylations

Angew Chem Int Ed Engl. 2016 Jun 1;55(23):6671-5. doi: 10.1002/anie.201601197. Epub 2016 Apr 25.

Authors

Xiaoyong Du¹, Yanlu Zhang¹, Dongjie Peng¹, Zheng Huang²

Affiliations

¹ State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, 345 Lingling Road, Shanghai, 200032, China.
² State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, 345 Lingling Road, Shanghai, 200032, China. huangzh@sioc.ac.cn.

PMID: 27111001
DOI: 10.1002/anie.201601197

Abstract

A complementary set of base metal catalysts has been developed for regiodivergent alkene hydrosilylations: iron complexes of phosphine-iminopyridine are selective for anti-Markovnikov hydrosilylations (linear/branched up to >99:1), while the cobalt complexes bearing the same type of ligands provide an unprecedented high level of Markovnikov selectivity (branched/linear up to >99:1). Both systems exhibit high efficiency and wide functional group tolerance.

Keywords: alkenes; cobalt; homogeneous catalysis; hydrosilylation; iron.

Publication types

Research Support, Non-U.S. Gov't