Turning off the BCL-2 switch to prevent intestinal tumorigenesis

Oncotarget. 2016 May 17;7(20):28763-4. doi: 10.18632/oncotarget.8757.
No abstract available

Keywords: Bcl-2; apoptosis; chemoprevention; colorectal carcinoma; intestinal stem cells.

Publication types

  • Editorial

MeSH terms

  • Adenoma / drug therapy
  • Adenoma / genetics
  • Adenoma / pathology
  • Adenoma / prevention & control
  • Animals
  • Apoptosis / drug effects
  • Cell Transformation, Neoplastic / drug effects*
  • Cell Transformation, Neoplastic / pathology*
  • Colorectal Neoplasms / drug therapy*
  • Colorectal Neoplasms / genetics
  • Colorectal Neoplasms / pathology
  • Colorectal Neoplasms / prevention & control*
  • Disease Models, Animal
  • Mice
  • Proto-Oncogene Proteins c-bcl-2 / antagonists & inhibitors*
  • Proto-Oncogene Proteins c-bcl-2 / deficiency*
  • Proto-Oncogene Proteins c-bcl-2 / metabolism

Substances

  • Proto-Oncogene Proteins c-bcl-2