Antissaliva Antibodies of Lutzomyia Longipalpis in area of Visceral Leishmaniasis

Pediatr Infect Dis J. 2016 Jul;35(7):805-7. doi: 10.1097/INF.0000000000001172.

Abstract

The aim of the present study was to assess the presence of antissaliva antibodies of Lutzomyia longipalpis in human hosts living in area of visceral leishmaniasis, located in the Center-West region of Brazil. The presence of antissaliva antibodies of L. longipalpis exhibited a strong correlation with the protection and development of antibodies against Leishmania sp. Of the 492 children studied, elevated antissaliva antibodies of L. longipalpis were detected in 38.4% of the participants. There was a higher percentage of positivity (64.7%) among children who exhibited anti-Leishmania sp. antibodies and among those who were positive in the delayed hypersensitivity test (34.8%).

MeSH terms

  • Adolescent
  • Animals
  • Antibodies / blood*
  • Antibodies / isolation & purification
  • Antibodies, Protozoan / immunology
  • Brazil
  • Child
  • Child, Preschool
  • Dog Diseases / parasitology
  • Dogs
  • Female
  • Humans
  • Hypersensitivity, Delayed / immunology
  • Insect Vectors
  • Leishmaniasis, Visceral / immunology*
  • Leishmaniasis, Visceral / parasitology
  • Leishmaniasis, Visceral / prevention & control
  • Male
  • Psychodidae / immunology*
  • Psychodidae / parasitology
  • Saliva / chemistry
  • Saliva / immunology*
  • Salivary Glands / immunology
  • Salivary Glands / metabolism
  • Salivary Proteins and Peptides / chemistry
  • Salivary Proteins and Peptides / immunology*

Substances

  • Antibodies
  • Antibodies, Protozoan
  • Salivary Proteins and Peptides