Various difunctionalizations of acrylamide: an efficient approach to synthesize oxindoles

Chen-Chen Li; Shang-Dong Yang

doi:10.1039/c6ob00554c

Various difunctionalizations of acrylamide: an efficient approach to synthesize oxindoles

Org Biomol Chem. 2016 May 11;14(19):4365-77. doi: 10.1039/c6ob00554c.

Authors

Chen-Chen Li¹, Shang-Dong Yang²

Affiliations

¹ State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P. R. China. yangshd@lzu.edu.cn and Cuiying Honors College, Lanzhou University, Lanzhou 730000, P. R. China.
² State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P. R. China. yangshd@lzu.edu.cn and State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, P. R. China.

PMID: 27091597
DOI: 10.1039/c6ob00554c

Abstract

Various difunctionalizations of acrylamide can not only provide a simple approach to form a wide scope of functionalized oxindoles, but can also be applied and generated easily. This review concludes different difunctionalizations of acrylamide to synthesize oxindoles based on the mechanistic aspects. The goal is to encourage further mechanistic studies hopefully leading to an in-depth understanding of this strategy.

Publication types

Review