Poly(L-lactide)/branched β-cyclodextrin blends: Thermal, morphological and mechanical properties

E Lizundia; F Gómez-Galván; L Pérez-Álvarez; L M León; J L Vilas

doi:10.1016/j.carbpol.2016.02.043

Poly(L-lactide)/branched β-cyclodextrin blends: Thermal, morphological and mechanical properties

Carbohydr Polym. 2016 Jun 25:144:25-32. doi: 10.1016/j.carbpol.2016.02.043. Epub 2016 Feb 18.

Authors

E Lizundia¹, F Gómez-Galván², L Pérez-Álvarez³, L M León⁴, J L Vilas⁵

Affiliations

¹ Macromolecular Chemistry Research Group, Dept. of Physical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Spain. Electronic address: erlantz.liizundia@ehu.es.
² Macromolecular Chemistry Research Group, Dept. of Physical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Spain. Electronic address: floresther_gomez001@ehu.es.
³ Macromolecular Chemistry Research Group, Dept. of Physical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Spain; Basque Center for Materials, Applications and Nanostructures (BCMaterials), Parque Tecnológico de Bizkaia, Ed. 500, Derio 48160, Spain. Electronic address: leyre.perez@ehu.eus.
⁴ Macromolecular Chemistry Research Group, Dept. of Physical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Spain; Basque Center for Materials, Applications and Nanostructures (BCMaterials), Parque Tecnológico de Bizkaia, Ed. 500, Derio 48160, Spain. Electronic address: luismanuel.leon@ehu.eus.
⁵ Macromolecular Chemistry Research Group, Dept. of Physical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Spain; Basque Center for Materials, Applications and Nanostructures (BCMaterials), Parque Tecnológico de Bizkaia, Ed. 500, Derio 48160, Spain. Electronic address: joseluis.vilas@ehu.eus.

PMID: 27083789
DOI: 10.1016/j.carbpol.2016.02.043

Abstract

In this work we develop poly(L-lactide)/branched β-cyclodextrin (bβCD) blends in an attempt to obtain new biocompatible and biodegradable materials to be used in the emerging fields of pharmaceutical, biomedicine and food industry. Ionic branched β-cyclodextrin (bβCD) was obtained by polycondensation of the β-CD monomer and it was blended with a commercially available PLLA. Fourier transform infrared spectroscopy (FTIR) has been applied to study the occurring interactions between both partners. Thermal properties of blends have been analyzed by differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA), while the phase structure of the blends was analyzed by scanning electron microscopy (SEM). Finally, dynamic mechanical analysis (DMA) has been used to provide further insights into the features controlling miscibility between PLLA and bβCD. Results show the presence of a single phase irrespectively of the blend composition. Overall, this work opens new perspectives for the development of naturally available materials with tunable functional properties for applications in which cyclodextrins emerge as a new class of promising candidates.

Keywords: Beta-cyclodextrin (PubChem CID: 444041); Branched β-cyclodextrin; Epichlorohydrin (PubChem CID: 7835); Glass transition temperature; Hydrochloric acid (PubChem CID: 313); L-lactic acid (PubChem CID: 107689); Miscibility; N,N-Dimethylformamide (PubChem CID: 6228); Poly(L-lactide); Polymer blend; Sodium hydroxide (PubChem CID: 14798); β-Cyclodextrin.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Calorimetry, Differential Scanning
Epichlorohydrin / chemistry
Hydrophobic and Hydrophilic Interactions
Mechanical Phenomena
Microscopy, Electron, Scanning
Polyesters / chemistry*
Proton Magnetic Resonance Spectroscopy
Spectroscopy, Fourier Transform Infrared
Stereoisomerism
Surface Properties
Temperature
beta-Cyclodextrins / chemical synthesis
beta-Cyclodextrins / chemistry*

Substances

Polyesters
beta-Cyclodextrins
Epichlorohydrin
poly(lactide)