Analysis and Outcomes of Cataract Surgery in Patients with Acquired Immunodeficiency Syndrome

Ocul Immunol Inflamm. 2017 Aug;25(4):535-539. doi: 10.3109/09273948.2016.1158281. Epub 2016 Apr 15.

Abstract

Purpose: To investigate the surgical outcomes, complications and postoperative progression in HIV patients undergoing cataract surgery in a teaching hospital.

Methods: A retrospective cohort study of patients with HIV/AIDS who had cataract surgery from January 2000 until December 2011 at a tertiary referral multidisciplinary hospital in Singapore.

Results: We identified 44 eyes from 29 patients. Preoperatively, 41.3% had no ophthalmic manifestations of HIV/AIDS, while 16 eyes had quiescent cytomegalovirus retinitis (CMVR). Postoperatively, 1 eye developed new CMVR, while 1 eye had reactivation of previous CMVR. Of eyes with new or previous CMVR, 1 eye developed rhegmatogenous retinal detachment (RD) postoperatively. Only 3 eyes had prolonged postoperative inflammation. There were no cases of endophthalmitis or cystoid macular edema. Postoperative improvement of at least two Snellen lines was achieved in 86.6% of eyes.

Conclusions: Cataract surgery in HIV patients is generally safe, regardless of CD4 count, but their general and ocular health should be optimized preoperatively.

Keywords: Cataract; HIV/AIDS; complications; cytomegalovirus retinitis; surgery.

MeSH terms

  • Acquired Immunodeficiency Syndrome / complications*
  • Acquired Immunodeficiency Syndrome / physiopathology
  • Adult
  • Aged
  • CD4 Lymphocyte Count
  • Cataract / complications*
  • Cataract / physiopathology
  • Cytomegalovirus Retinitis / complications
  • Cytomegalovirus Retinitis / physiopathology
  • Female
  • Humans
  • Intraoperative Complications
  • Lens Implantation, Intraocular*
  • Male
  • Middle Aged
  • Phacoemulsification*
  • Postoperative Complications
  • Pseudophakia / physiopathology
  • Retrospective Studies
  • Singapore
  • Tertiary Care Centers
  • Treatment Outcome
  • Visual Acuity / physiology