Data for accelerated degradation of calcium phosphate surface-coated polycaprolactone and polycaprolactone/bioactive glass composite scaffolds

Patrina S P Poh; Dietmar W Hutmacher; Boris M Holzapfel; Anu K Solanki; Maria A Woodruff

doi:10.1016/j.dib.2016.01.023

Data for accelerated degradation of calcium phosphate surface-coated polycaprolactone and polycaprolactone/bioactive glass composite scaffolds

Data Brief. 2016 Jan 22:7:923-6. doi: 10.1016/j.dib.2016.01.023. eCollection 2016 Jun.

Authors

Patrina S P Poh¹, Dietmar W Hutmacher², Boris M Holzapfel³, Anu K Solanki⁴, Maria A Woodruff⁵

Affiliations

¹ Institute of Health and Biomedical Innovation, Queensland University of Technology, 60 Musk Avenue, Kelvin Grove, 4059 Brisbane, Australia; Department of Experimental Trauma Surgery, Klinikum Rechts der Isar, Technical University Munich, Ismaninger 22, 81675 Munich, Germany.
² Institute of Health and Biomedical Innovation, Queensland University of Technology, 60 Musk Avenue, Kelvin Grove, 4059 Brisbane, Australia; Institute for Advanced Study, Technical University Munich, Lichtenbergstrasse 2a, 85748 Garching, Munich, Germany.
³ Institute of Health and Biomedical Innovation, Queensland University of Technology, 60 Musk Avenue, Kelvin Grove, 4059 Brisbane, Australia; Department of Orthopaedic Surgery, Koenig-Ludwig Haus, University of Wuerzburg, Brettreichstr. 11, 97074 Wuerzburg, Germany.
⁴ Department of Materials and Department of Bioengineering, Institute of Biomedical Engineering, Imperial College London, Exhibition Road, London SW7 2AZ, United Kingdom.
⁵ Institute of Health and Biomedical Innovation, Queensland University of Technology, 60 Musk Avenue, Kelvin Grove, 4059 Brisbane, Australia.

Abstract

Polycaprolactone (PCL)-based composite scaffolds containing 50 wt% of 45S5 bioactive glass (45S5) or strontium-substituted bioactive glass (SrBG) particles were fabricated into scaffolds using melt-extrusion based additive manufacturing technique. Additionally, the PCL scaffolds were surface coated with a layer of calcium phosphate (CaP). For a comparison of the scaffold degradation, the scaffolds were then subjected to in vitro accelerated degradation by immersion in 5 M sodium hydroxide (NaOH) solution for up to 7 days. The scaffold׳s morphology was observed by means of SEM imaging and scaffold mass loss was recorded over the experimental period.