Data on keratin expression in human cells cultured with Australian native plant extracts

Damian H Adams; Qingyao Shou; Hans Wohlmuth; Allison J Cowin

doi:10.1016/j.dib.2016.02.069

Data on keratin expression in human cells cultured with Australian native plant extracts

Data Brief. 2016 Mar 18:7:848-67. doi: 10.1016/j.dib.2016.02.069. eCollection 2016 Jun.

Authors

Damian H Adams¹, Qingyao Shou², Hans Wohlmuth³, Allison J Cowin¹

Affiliations

¹ Regenerative Medicine, Future Industries Institute, University of South Australia, Mawson Lakes, South Australia 5095, Australia.
² Southern Cross Plant Science, Southern Cross University, Lismore, New South Wales 2480, Australia.
³ Southern Cross Plant Science, Southern Cross University, Lismore, New South Wales 2480, Australia; Integria Healthcare, Gallans Road, Ballina, New South Wales 2478, Australia.

Abstract

Australian native plants have a long history of therapeutic use in indigenous cultures particularly for the treatment of wounds. We analysed 14 plant derived compounds from the species Pilidiostigma glabrum, Myoporum montanum, Geijera parviflora, and Rhodomyrtus psidioides for keratin 1, 5, 10 and 14 supporting the research article "Native Australian plant extracts differentially induce Collagen I and Collagen III in vitro and could be important targets for the development of new wound healing therapies" [5]. An in situ immunofluorescence assay was used in a 96 well tissue culture plate format to measure keratin expression in immortalised human keratinocytes (HaCaTs) exposed Australian native plant compounds to NMR spectra for the plant extracts are included in this article as is quantitative fluorescent intensity data of keratin 1, 5, 10 and 14 expression.