Microbiome: Eating for trillions

Nature. 2016 Apr 21;532(7599):316-7. doi: 10.1038/nature17887. Epub 2016 Apr 13.

Abstract

Three studies investigate the bacteria in the guts of malnourished children and find that, when this microbiota is transferred into mice, supplements of certain microbes or sugars from human breast milk can restore normal growth.

MeSH terms

  • Animals
  • Child, Preschool
  • Chronic Disease
  • Clostridium symbiosum / isolation & purification
  • Clostridium symbiosum / physiology
  • Diet / adverse effects
  • Diet / methods
  • Feces / microbiology
  • Female
  • Germ-Free Life
  • Growth Disorders / diet therapy*
  • Growth Disorders / etiology
  • Growth Disorders / microbiology*
  • Healthy Volunteers
  • Humans
  • Infant
  • Intestines / drug effects
  • Intestines / microbiology*
  • Liver / metabolism
  • Malawi
  • Malnutrition / complications
  • Malnutrition / diet therapy*
  • Malnutrition / microbiology*
  • Mice
  • Microbiota / drug effects
  • Microbiota / genetics
  • Microbiota / physiology*
  • Milk, Human / chemistry
  • Milk, Human / microbiology
  • Mothers
  • Oligosaccharides / analysis
  • Oligosaccharides / pharmacology
  • Oligosaccharides / therapeutic use
  • Ruminococcus / isolation & purification
  • Ruminococcus / physiology
  • Somatomedins / biosynthesis
  • Weight Gain / drug effects

Substances

  • Oligosaccharides
  • Somatomedins