Diabetic retinopathy in pregnancy: a review

Clin Exp Ophthalmol. 2016 May;44(4):321-34. doi: 10.1111/ceo.12760. Epub 2016 May 17.

Abstract

The prevalence of diabetes in pregnancy is increasing. Pre-existing diabetes is present in 1 in 167 pregnancies in Australia, divided equally between type 1 and type 2 diabetes. Diabetic retinopathy is a leading cause of blindness in women during their childbearing years, and pregnancy increases the short-term risk of diabetic retinopathy progression. We examine the risk factors for progression of diabetic retinopathy during pregnancy including duration of diabetes, baseline level of retinopathy, level of glycaemic control and hypertension. We also examine current screening and management guidelines and their levels of evidence, current treatment options for diabetic retinopathy and avenues for further research.

Keywords: diabetic retinopathy; pre-existing diabetes; pregnancy; prevalence.

Publication types

  • Review

MeSH terms

  • Adult
  • Diabetes Mellitus, Type 1 / epidemiology
  • Diabetes Mellitus, Type 1 / physiopathology
  • Diabetes Mellitus, Type 2 / epidemiology
  • Diabetes Mellitus, Type 2 / physiopathology
  • Diabetic Retinopathy / diagnosis
  • Diabetic Retinopathy / epidemiology
  • Diabetic Retinopathy / physiopathology*
  • Disease Progression
  • Female
  • Humans
  • Pregnancy
  • Pregnancy in Diabetics / diagnosis
  • Pregnancy in Diabetics / epidemiology
  • Pregnancy in Diabetics / physiopathology*
  • Risk Factors