Telocytes in female reproductive system (human and animal)

J Cell Mol Med. 2016 Jun;20(6):994-1000. doi: 10.1111/jcmm.12843. Epub 2016 Apr 5.

Abstract

Telocytes (TCs) are a newly discovered type of cell with numerous functions. They have been found in a large variety of organs: heart (endo-, myo-, epi- and pericardium, myocardial sleeves, heart valves); digestive tract and annex glands (oesophagus, stomach, duodenum, jejunum, liver, gallbladder, salivary gland, exocrine pancreas); respiratory system (trachea and lungs); urinary system (kidney, renal pelvis, ureters, bladder, urethra); female reproductive system (uterus, Fallopian tube, placenta, mammary gland); vasculature (blood vessels, thoracic duct); serous membranes (mesentery and pleura); and other organs (skeletal muscle, meninges and choroid plexus, neuromuscular spindles, fascia lata, skin, eye, prostate, bone marrow). Likewise, TCs are widely distributed in vertebrates (fish, reptiles, birds, mammals, including human). This review summarizes particular features of TCs in the female reproductive system, emphasizing their involvement in physiological and pathophysiological processes.

Keywords: CD34; Fallopian tube; human placenta; myometrium; sex steroid receptors; telocytes; telopodes; uterus.

Publication types

  • Review

MeSH terms

  • Animals
  • Electrophysiological Phenomena
  • Female
  • Gene Expression Profiling
  • Humans
  • Immunohistochemistry
  • Lasers
  • Reproduction*
  • Telocytes / metabolism*