Abstract
RNA polymerase III (RNAPIII) synthesizes diverse, small, non-coding RNAs with many important roles in the cellular metabolism. One of the open questions of RNAPIII transcription is whether and how additional factors are involved. Recently, Nab2 was identified as the first messenger ribonucleoprotein particle (mRNP) biogenesis factor with a function in RNAPIII transcription.
Keywords:
Nab2; RNA polymerase III; TFIIIB; ZC3H14; gene expression; ncRNA; tRNA; transcription.
MeSH terms
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Nucleocytoplasmic Transport Proteins / metabolism*
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RNA Polymerase II / metabolism
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RNA Polymerase III / metabolism*
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RNA Stability
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RNA, Fungal / chemistry
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RNA, Fungal / metabolism
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RNA, Untranslated / chemistry
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RNA, Untranslated / metabolism
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RNA-Binding Proteins / metabolism*
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Saccharomyces cerevisiae / genetics
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Saccharomyces cerevisiae / metabolism*
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Saccharomyces cerevisiae Proteins / metabolism*
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Transcription, Genetic*
Substances
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NAB2 protein, S cerevisiae
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Nucleocytoplasmic Transport Proteins
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RNA, Fungal
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RNA, Untranslated
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RNA-Binding Proteins
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Saccharomyces cerevisiae Proteins
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RNA Polymerase II
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RNA Polymerase III