The current place of probiotics and prebiotics in the treatment of pouchitis

Lev Lichtenstein; Irit Avni-Biron; Ofer Ben-Bassat

doi:10.1016/j.bpg.2016.02.003

The current place of probiotics and prebiotics in the treatment of pouchitis

Best Pract Res Clin Gastroenterol. 2016 Feb;30(1):73-80. doi: 10.1016/j.bpg.2016.02.003. Epub 2016 Feb 9.

Authors

Lev Lichtenstein¹, Irit Avni-Biron², Ofer Ben-Bassat²

Affiliations

¹ Rabin Medical Center, Petah Tikva, Israel; Sackler Faculty of Medicine, University of Tel Aviv, Israel. Electronic address: levl@clalit.org.il.
² Rabin Medical Center, Petah Tikva, Israel; Sackler Faculty of Medicine, University of Tel Aviv, Israel.

PMID: 27048898
DOI: 10.1016/j.bpg.2016.02.003

Abstract

Pouchitis is a common complication in patients undergoing restorative proctocolectomy for ulcerative colitis. Therapeutic attempts include manipulations of pouch flora composition. In this review, we bring together the evidence supporting the use of probiotics and prebiotics in pouchitis patients, to clarify the place of these treatments in current therapeutic regimens.

Keywords: Bifidobacterium; Inflammatory bowel disease; Lactobacillus; Pouchitis; Prebiotics; Probiotics; Sacchromyces boullardi; Synbiotics; Ulcerative colitis; VSL#3.

Publication types

Review

MeSH terms

Colitis, Ulcerative / therapy
Gastrointestinal Microbiome / physiology
Gastrointestinal Tract / microbiology
Humans
Pouchitis / therapy*
Prebiotics / microbiology*
Probiotics / therapeutic use*
Proctocolectomy, Restorative

Substances

Prebiotics