Phylogenetic analysis of the glycoprotein gene of viral hemorrhagic septicemia virus from Iranian trout farms points towards a common European origin

Vet Microbiol. 2016 Apr 15:186:97-101. doi: 10.1016/j.vetmic.2016.02.019. Epub 2016 Feb 26.

Abstract

Viral haemorrhagic septicaemia virus (VHSV), a member of family Rhabdoviridae and genus Novirhabdoviridae, causes mortality in numerous marine and freshwater hosts located in northern hemisphere. To evaluate the genetic diversity of VHSV from the North and South West of Iran, the sequences of a 1483bp nt region of the glycoprotein gene were determined for four Iranian isolates. These sequences were analysed to evaluate their genetic relatedness with 86 worldwide isolates representing the four known genogroups of VHSV. Phylogenetic analysis by nucleotide sequences showed that all the VHSV isolates studied were closest related to the 19 fresh water strains from Germany grouped within the European genogroup Ia-2. This finding indicates that Iranian VHSV most likely was introduced to Iran by the movement of contaminated fish fry from a source in Europe.

Keywords: Genetic relatedness; Glycoprotein gene; Iran; Rainbow trout; Trading practice.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Europe / epidemiology
  • Glycoproteins / genetics*
  • Hemorrhagic Septicemia, Viral / epidemiology
  • Hemorrhagic Septicemia, Viral / mortality
  • Hemorrhagic Septicemia, Viral / virology*
  • Iran / epidemiology
  • Novirhabdovirus / classification*
  • Novirhabdovirus / genetics
  • Novirhabdovirus / isolation & purification
  • Oncorhynchus mykiss / virology
  • Phylogeny*

Substances

  • Glycoproteins