Suppression of melanin synthesis by Americanin A in melan-a cells via regulation of microphthalmia-associated transcription factor

Exp Dermatol. 2016 Aug;25(8):646-7. doi: 10.1111/exd.13013. Epub 2016 Jun 1.

Authors

Yoonho Shin¹, Eun Jung Jang¹, Hyen Joo Park¹, Ji-Young Hong¹, Sam Sik Kang¹, Sang Kook Lee¹

Affiliation

¹ College of Pharmacy, Natural Products Research Institute, Seoul National University, Seoul, 151-742, Korea.

PMID: 26997427
DOI: 10.1111/exd.13013

No abstract available

Keywords: c-kit; melanogenesis; microphthalmia-associated transcription factor (MITF); natural lignan; tyrosinase.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cell Line
Dioxins / pharmacology*
Drug Evaluation, Preclinical
Melanins / biosynthesis*
Melanocytes / drug effects*
Melanocytes / metabolism
Mice
Microphthalmia-Associated Transcription Factor / metabolism*
Monophenol Monooxygenase / metabolism
Skin Lightening Preparations / pharmacology*

Substances

Dioxins
Melanins
Microphthalmia-Associated Transcription Factor
Mitf protein, mouse
Skin Lightening Preparations
americanin A
Monophenol Monooxygenase