Data on in vitro and in vivo cell orientation on substrates with different topographies

Andrew English; Ayesha Azeem; Kyriakos Spanoudes; Eleanor Jones; Bhawana Tripathi; Nandita Basu; Karrina McNamara; Syed A M Tofail; Niall Rooney; Graham Riley; Alan O'Riordan; Graham Cross; Dietmar Hutmacher; Manus Biggs; Abhay Pandit; Dimitrios I Zeugolis

doi:10.1016/j.dib.2015.09.024

Data on in vitro and in vivo cell orientation on substrates with different topographies

Data Brief. 2015 Oct 1:5:379-82. doi: 10.1016/j.dib.2015.09.024. eCollection 2015 Dec.

Authors

Affiliations

¹ Regenerative, Modular & Developmental Engineering Laboratory (REMODEL), Biosciences Research Building (BRB), National University of Ireland Galway, NUI Galway, Galway, Ireland; Network of Excellence for Functional Biomaterials (NFB), BRB, NUI Galway, Galway, Ireland; Centre for Research in Medical Devices (CÚRAM), BRB, NUI Galway, Galway, Ireland.
² School of Biological Sciences, University of East Anglia, Norwich, UK.
³ Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN), Trinity College Dublin, Dublin, Ireland.
⁴ Materials and Surface Science Institute (MSSI), Department of Physics and Energy, University of Limerick, Limerick, Ireland.
⁵ Proxy Biomedical, Galway, Ireland.
⁶ Tyndall National Institute, Cork, Ireland.
⁷ Institute of Health & Biomedical Innovation, Queensland University of Technology, Australia.
⁸ Network of Excellence for Functional Biomaterials (NFB), BRB, NUI Galway, Galway, Ireland; Centre for Research in Medical Devices (CÚRAM), BRB, NUI Galway, Galway, Ireland.

Abstract

This data article contains data related to the research article entitled "Substrate topography: A valuable in vitro tool, but a clinical red herring for in vivo tenogenesis" [1]. We report measurements on tenocyte viability, metabolic activity and proliferation on substrates with different topographies. We also report the effect of substrates with different topographies on host cells in a subcutaneous model.

Keywords: Anisotropic substrates; Imprinting; Subcutaneous model; Tenocytes.