Sepsis management: An evidence-based approach

J Pak Med Assoc. 2016 Mar;66(3):337-8.

Abstract

The Surviving Sepsis Campaign (SSC) guidelines have outlined an early goal directed therapy (EGDT) which demonstrates a standardized approach to ensure prompt and effective management of sepsis. Having said that, there are barriers associated with the application of evidence-based practice, which often lead to an overall poorer adherence to guidelines. Considering the global burden of disease, data from low- to middle-income countries is scarce. Asia is the largest continent but most Asian countries do not have a well-developed healthcare system and compliance rates to resuscitation and management bundles are as low as 7.6% and 3.5%, respectively. Intensive care units are not adequately equipped and financial concerns limit implementation of expensive treatment strategies. Healthcare policy-makers should be notified in order to alleviate financial restrictions and ensure delivery of standard care to septic patients.

Keywords: Sepsis in Asia, Early Goal Directed therapy (EGDT), Sepsis resuscitation bundle, Sepsis management bundle..

MeSH terms

  • Asia
  • Clinical Protocols
  • Disease Management
  • Evidence-Based Medicine*
  • Guideline Adherence
  • Humans
  • Intensive Care Units
  • Patient Care Bundles / methods*
  • Practice Guidelines as Topic
  • Resuscitation
  • Sepsis / therapy*