Cas9 loosens its grip on off-target sites

Nat Biotechnol. 2016 Mar;34(3):298-9. doi: 10.1038/nbt.3501.
No abstract available

MeSH terms

  • Bacterial Proteins / genetics*
  • CRISPR-Associated Protein 9
  • DNA / genetics*
  • Endonucleases / genetics*
  • Gene Targeting*
  • Genome, Human
  • Humans
  • RNA Editing*
  • Streptococcus pyogenes / enzymology
  • Streptococcus pyogenes / genetics

Substances

  • Bacterial Proteins
  • DNA
  • CRISPR-Associated Protein 9
  • Cas9 endonuclease Streptococcus pyogenes
  • Endonucleases