The Kidney in Critical Cardiac Disease: Proceedings From the 10th International Conference of the Pediatric Cardiac Intensive Care Society

David S Cooper; Rajit K Basu; Jack F Price; Stuart L Goldstein; Catherine D Krawczeski

doi:10.1177/2150135115623289

The Kidney in Critical Cardiac Disease: Proceedings From the 10th International Conference of the Pediatric Cardiac Intensive Care Society

World J Pediatr Congenit Heart Surg. 2016 Mar;7(2):152-63. doi: 10.1177/2150135115623289.

Authors

David S Cooper¹, Rajit K Basu², Jack F Price³, Stuart L Goldstein⁴, Catherine D Krawczeski⁵

Affiliations

¹ The Heart Institute and the Center for Acute Care Nephrology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA david.cooper@cchmc.org.
² Division of Critical Care and the Center for Acute Care Nephrology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
³ Division of Cardiology, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
⁴ The Heart Institute and the Center for Acute Care Nephrology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
⁵ Dvision of Cardiology, Lucile Packard Children's Hospital, Stanford University, Palo Alto, CA, USA.

PMID: 26957397
DOI: 10.1177/2150135115623289

Abstract

The field of cardiac intensive care continues to advance in tandem with congenital heart surgery. The focus of intensive care unit care has now shifted to that of morbidity reduction and eventual elimination. Acute kidney injury (AKI) after cardiac surgery is associated with adverse outcomes, including prolonged intensive care and hospital stays, diminished quality of life, and increased long-term mortality. Acute kidney injury occurs frequently, complicating the care of both postoperative patients and those with heart failure. Patients who become fluid overloaded and/or require dialysis are at high risk of mortality, but even minor degrees of AKI portend a significant increase in mortality and morbidity. Clinicians continue to seek methods of early diagnosis and risk stratification of AKI to prevent its adverse sequelae. Previous conventional wisdom that survivors of AKI fully recover renal function without subsequent consequences may be flawed.

Keywords: acute kidney injury; chronic kidney disease; congenital heart disease; congenital heart surgery; fluid overload; renal replacement therapy.

Publication types

Congress

MeSH terms

Acute Kidney Injury / diagnosis
Acute Kidney Injury / epidemiology*
Acute Kidney Injury / therapy
Cardiac Surgical Procedures*
Cardio-Renal Syndrome*
Cardiopulmonary Bypass
Child
Coronary Care Units
Disease Progression
Early Diagnosis
Heart Defects, Congenital / surgery*
Heart Failure
Humans
Intensive Care Units, Pediatric
Length of Stay
Postoperative Complications / epidemiology*
Postoperative Complications / therapy
Prognosis
Quality of Life
Renal Dialysis
Renal Insufficiency, Chronic / epidemiology*
Risk Assessment
Severity of Illness Index
Water-Electrolyte Imbalance / epidemiology*
Water-Electrolyte Imbalance / therapy