Eosinophilic colitis

BMJ Case Rep. 2016 Mar 8:2016:bcr2016214496. doi: 10.1136/bcr-2016-214496.

Abstract

A 57-year-old man, diagnosed with colon cancer stage III in July/2010, underwent surgery and received adjuvant chemotherapy with FOLFOX 4 (5-fluorouracil; calcium folinate and oxaliplatin), which ended in March/2011 after 12-cycles. It was then decided to maintain periodical surveillance. About 1 year later, the patient developed several episodes of diarrhoea, mainly during the night, and presented persistent peripheral eosinophilia in the blood count (range 585-1300 eosinophils/µL). Colonoscopy was performed, with the histological result showing eosinophilic infiltration of the colon, compatible with eosinophilic colitis. The patient was treated with a short course of budesonide, achieving resolution of symptoms, and has remained asymptomatic.

Publication types

  • Case Reports

MeSH terms

  • Budesonide / therapeutic use
  • Colitis / diagnosis*
  • Colitis / drug therapy*
  • Colonoscopy
  • Eosinophilia / diagnosis*
  • Eosinophilia / drug therapy*
  • Glucocorticoids / therapeutic use
  • Humans
  • Male
  • Middle Aged
  • Treatment Outcome

Substances

  • Glucocorticoids
  • Budesonide