Synthetic studies toward citrinadin A: construction of the pentacyclic core

J Antibiot (Tokyo). 2016 Apr;69(4):331-6. doi: 10.1038/ja.2016.25. Epub 2016 Mar 9.

Abstract

This manuscript describes the preparation of an advanced intermediate toward the total synthesis of citrinadin A, featuring a [3+2] cycloaddition employing in situ generation of the dipole.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Cycloaddition Reaction
  • Indole Alkaloids / chemical synthesis*
  • Indole Alkaloids / chemistry
  • Molecular Structure
  • Stereoisomerism

Substances

  • Indole Alkaloids
  • citrinadin A