Innovations in Small-Animal PET/MR Imaging Instrumentation

Abstract

Multimodal imaging has led to a more detailed exploration of different physiologic processes with integrated PET/MR imaging being the most recent entry. Although the clinical need is still questioned, it is well recognized that it represents one of the most active and promising fields of medical imaging research in terms of software and hardware. The hardware developments have moved from small detector components to high-performance PET inserts and new concepts in full systems. Conversely, the software focuses on the efficient performance of necessary corrections without the use of CT data. The most recent developments in both directions are reviewed.

Keywords: Attenuation correction; Input function; Kinetic modeling; Low dose; Motion correction; PET/MR imaging; Silicon photomultiplier; Time of flight.