Evaluation of CFH Y402H polymorphism and CFHR3/CFHR1 deletion in age-related macular degeneration patients from Brazil

Ophthalmic Genet. 2016 Dec;37(4):459-461. doi: 10.3109/13816810.2015.1120315. Epub 2016 Mar 4.

Authors

Daniela Prescila Dezidério Sacconi¹, José Paulo Cabral de Vasconcellos², Fábio Endo Hirata², Flávio MacCord Medina², Priscila Hae Hyun Rim², Mônica Barbosa de Melo¹

Affiliations

¹ a Laboratory of Human Genetics , Center of Molecular Biology and Genetic Engineering, University of Campinas , Campinas , SP , Brazil.
² b Department of Ophthalmology, Faculty of Medical Sciences , University of Campinas , Campinas , SP , Brazil.

PMID: 26942649
DOI: 10.3109/13816810.2015.1120315

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Blood Proteins / genetics*
Brazil
Chromosomes, Human, Pair 1 / genetics
Complement C3b Inactivator Proteins / genetics*
Complement Factor H / genetics
Female
Gene Deletion*
Geographic Atrophy / diagnosis
Geographic Atrophy / genetics*
Humans
Male
Polymerase Chain Reaction
Polymorphism, Single Nucleotide*
Wet Macular Degeneration / diagnosis
Wet Macular Degeneration / genetics*

Substances

Blood Proteins
CFH protein, human
CFHR1 protein, human
CFHR3 protein, human
Complement C3b Inactivator Proteins
Complement Factor H