Population data of 17 short tandem repeat loci in 2923 individuals from the Han population of Nantong in East China

Int J Legal Med. 2016 Sep;130(5):1195-7. doi: 10.1007/s00414-016-1332-5. Epub 2016 Mar 1.

Abstract

Nantong is located in mid-eastern China, and the Han population in Nantong may be greatly affected by population admixture between northern and southern Han Chinese populations. In this study, we analyzed 17 autosomal short tandem repeat (STR) loci on 2923 unrelated individuals collected from the Han population of Nantong. No significant deviation from Hardy-Weinberg equilibrium was observed at all STR loci, and the expected heterozygosity ranged from 0.6184 to 0.9187. The combined match probability (CMP) was 3.87 × 10(-21), and the combined power of discrimination (CPD) was 99.999999999999999999613 %. No significant difference of allele frequencies was observed between Nantong and other Han populations at all STR loci, as well as Dai, Mongolian, and Tibetan. Significant differences were only observed between Nantong Han and Uyghur at TH01, as well as Nantong Han and Dong at CSF1PO and FGA. Nantong Han showed significant differences between She, Bouyei, and Miao at multiple STR loci.

Keywords: Han; Nantong; Short tandem repeat.

MeSH terms

  • China
  • DNA Fingerprinting
  • Ethnicity / genetics*
  • Gene Frequency
  • Genetics, Population*
  • Humans
  • Microsatellite Repeats*
  • Polymorphism, Genetic