Cobalt(II)-Catalyzed C-H Amination of Arenes with Simple Alkylamines

Lin-Bao Zhang; Shou-Kun Zhang; Donghui Wei; Xinju Zhu; Xin-Qi Hao; Jian-Hang Su; Jun-Long Niu; Mao-Ping Song

doi:10.1021/acs.orglett.6b00241

Cobalt(II)-Catalyzed C-H Amination of Arenes with Simple Alkylamines

Org Lett. 2016 Mar 18;18(6):1318-21. doi: 10.1021/acs.orglett.6b00241. Epub 2016 Feb 29.

Authors

Lin-Bao Zhang¹, Shou-Kun Zhang¹, Donghui Wei¹, Xinju Zhu¹, Xin-Qi Hao¹, Jian-Hang Su¹, Jun-Long Niu¹, Mao-Ping Song¹

Affiliation

¹ The College of Chemistry and Molecular Engineering, Zhengzhou University , Zhengzhou 450001, P. R. China.

PMID: 26928948
DOI: 10.1021/acs.orglett.6b00241

Abstract

A new method of cobalt-catalyzed amination of arylamides with simple alkylamines is reported through C(sp(2))-H bond functionalization. For the first time, inexpensive cobalt is exploited as the catalyst in the amination of C(sp(2))-H bond using simple alkylamines.

Publication types

Research Support, Non-U.S. Gov't