Risk Factors for Early Failure of Arteriovenous Vascular Access Among Patients With Type 2 Diabetes Mellitus

Ther Apher Dial. 2016 Apr;20(2):112-7. doi: 10.1111/1744-9987.12383. Epub 2016 Feb 25.

Abstract

The aim of the study was to identify the potential risk factors for early arteriovenous access failure in a diabetic population. The data of 223 end-stage renal disease (ESRD) patients with type 2 diabetes who had an arteriovenous fistula (AVF) or arteriovenous graft (AVG) placed as their initial vascular accesses were retrospectively reviewed. The association between clinical factors and risk for early failure was then analyzed. In multivariate analysis, the predictors associated with early failure were female gender (odds ratio (95% confidence interval): 2.52 (1.32-4.81); P = 0.005), AVF with prior peritoneal dialysis (3.26 (1.05-10.11); P = 0.039), and lower hemoglobin level (P = 0.015). The results of significant predictors in the AVF group remained similar to the entire study population. In conclusion, there was an association of female gender, AVF with prior peritoneal dialysis and lower hemoglobin level with early arteriovenous access failure in a diabetic ESRD population.

Keywords: Early arteriovenous access failure; End-stage renal disease; Risk factors; Type 2 diabetes mellitus.

MeSH terms

  • Aged
  • Arteriovenous Shunt, Surgical / methods*
  • Diabetes Mellitus, Type 2 / complications*
  • Female
  • Hemoglobins / metabolism
  • Humans
  • Kidney Failure, Chronic / therapy*
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Peritoneal Dialysis / methods
  • Renal Dialysis / methods*
  • Retrospective Studies
  • Risk Factors
  • Sex Factors
  • Treatment Failure

Substances

  • Hemoglobins