Efficient continuous synthesis of high purity deep eutectic solvents by twin screw extrusion

D E Crawford; L A Wright; S L James; A P Abbott

doi:10.1039/c5cc09685e

Efficient continuous synthesis of high purity deep eutectic solvents by twin screw extrusion

Chem Commun (Camb). 2016 Mar 18;52(22):4215-8. doi: 10.1039/c5cc09685e.

Authors

D E Crawford¹, L A Wright², S L James¹, A P Abbott²

Affiliations

¹ School of Chemistry and Chemical Engineering, Queen's University Belfast, 39 - 123 Stranmillis Road, Belfast, BT9 5AG, Northern Ireland, UK. s.james@qub.ac.uk.
² Department of Chemistry, University of Leicester, Leicester, LE1 7RH, UK. apa1@le.ac.uk.

PMID: 26911554
DOI: 10.1039/c5cc09685e

Abstract

Mechanochemical synthesis has been applied to the rapid synthesis of Deep Eutectic Solvents (DESs), including Reline 200 (choline chloride : urea, 1 : 2), in a continuous flow methodology by Twin Screw Extrusion (TSE). This gave products in higher purity and with Space Time Yields (STYs), four orders of magnitude greater than for batch methods.

Publication types

Research Support, Non-U.S. Gov't