Characterization data of gilthead sea bream (Sparus aurata) IGF-I receptors (IGF-IRa/Rb)

Emilio J Vélez; Sheida Azizi; Cristina Salmerón; Shu Jin Chan; Mohammad Ali Nematollahi; Bagher Mojazi Amiri; Isabel Navarro; Encarnación Capilla; Joaquim Gutiérrez

doi:10.1016/j.dib.2015.12.046

Characterization data of gilthead sea bream (Sparus aurata) IGF-I receptors (IGF-IRa/Rb)

Data Brief. 2016 Jan 6:6:507-13. doi: 10.1016/j.dib.2015.12.046. eCollection 2016 Mar.

Authors

Emilio J Vélez¹, Sheida Azizi², Cristina Salmerón¹, Shu Jin Chan³, Mohammad Ali Nematollahi⁴, Bagher Mojazi Amiri⁴, Isabel Navarro¹, Encarnación Capilla¹, Joaquim Gutiérrez¹

Affiliations

¹ Departament de Fisiologia i Immunologia, Facultat de Biologia, Universitat de Barcelona, Avinguda Diagonal 643, 08028 Barcelona, Spain.
² Department of Fisheries Sciences, Faculty of Natural Resources, University of Tehran, Karaj, Iran; Departament de Fisiologia i Immunologia, Facultat de Biologia, Universitat de Barcelona, 08028 Barcelona, Spain. Visitor PhD student.
³ Department of Biochemistry and Molecular Biology and Department of Medicine and the Howard Hughes Medical Institute, University of Chicago, Chicago, IL 60637, USA.
⁴ Department of Fisheries Sciences, Faculty of Natural Resources, University of Tehran, Karaj, Iran.

Abstract

In this data article we describe the coding sequence of two IGF-IR paralogues (IGF-IRa and IGF-IRb) obtained from gilthead sea bream embryos. The putative protein architecture (domains and other important motifs) was determined and, amino acid sequences alignment and phylogenetic analysis of both receptors together with IGF-IR orthologues from different vertebrates was performed. Additionally, a semi-quantitative conventional PCR was done to analyze the mRNA expression of both receptors in different tissues of gilthead sea bream. These data will assist in further physiological studies in this species. In this sense, the expression of both receptors during ontogeny in muscle as well as the differential effects of IGF-I and IGF-II on their regulation during in vitro myogenesis has been recently studied (doi: 10.1016/j.ygcen.2015.11.011; [1]).

Keywords: Gilthead sea bream; IGF-I receptors.