Depression, Fatigue, and QoL in Colorectal Cancer Patients During and After Treatment

West J Nurs Res. 2016 Jul;38(7):893-908. doi: 10.1177/0193945916630256. Epub 2016 Feb 22.

Abstract

In this study, we sought to explore the prevalence of depression and fatigue in colorectal cancer patients during and after treatment to examine how these variables affect quality of life (QoL). In total, 170 patients with colorectal cancer participated in this study. The study population was divided into two groups: one receiving treatment and another that had finished treatment. The results showed that depression and fatigue measurements were higher in patients receiving treatment. Depression was a strong and significant predictor of QoL in both groups, whereas fatigue was not, with the exception of the symptom score. These findings underscore the importance of early detection and management of depression and fatigue during the treatment and survival stages of patients with colorectal cancer. Our findings indicate that health care professionals should provide appropriate nursing intervention to decrease depression and fatigue and enhance patient QoL.

Keywords: colorectal cancer; depression; fatigue; quality of life.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Colorectal Neoplasms* / drug therapy
  • Colorectal Neoplasms* / radiotherapy
  • Cross-Sectional Studies
  • Depression / epidemiology*
  • Fatigue / epidemiology*
  • Female
  • Humans
  • Male
  • Prevalence
  • Quality of Life*
  • Surveys and Questionnaires