Safety and technique of ferumoxytol administration for MRI

Magn Reson Med. 2016 May;75(5):2107-11. doi: 10.1002/mrm.26151. Epub 2016 Feb 18.

Abstract

Ferumoxytol is an ultrasmall superparamagnetic iron oxide agent marketed for the treatment of anemia. There has been increasing interest in its properties as an MRI contrast agent as well as greater awareness of its adverse event profile. This mini-review summarizes the current state of knowledge of the risks of ferumoxytol and methods of administration.

Keywords: contrast agent; ferumoxytol; iron oxide; safety.

Publication types

  • Review

MeSH terms

  • Clinical Trials as Topic
  • Contrast Media / chemistry
  • Ferric Compounds / chemistry
  • Ferrosoferric Oxide / administration & dosage*
  • Ferrosoferric Oxide / adverse effects
  • Ferrosoferric Oxide / chemistry
  • Gadolinium / chemistry
  • Humans
  • Iodine / chemistry
  • Macrophages / metabolism
  • Magnetic Resonance Imaging*
  • Neoplasm Metastasis
  • Neoplasms / diagnostic imaging*
  • Neoplasms / pathology*
  • Patient Safety
  • Perfusion

Substances

  • Contrast Media
  • Ferric Compounds
  • ferric oxide
  • Iodine
  • Gadolinium
  • Ferrosoferric Oxide