Stroke and sleep-disordered breathing: A relationship under construction

World J Clin Cases. 2016 Feb 16;4(2):33-7. doi: 10.12998/wjcc.v4.i2.33.

Abstract

The association between sleep-disordered breathing (SDB) and cardiovascular risk has been the focus of attention in recent years. Sleep disorders are emerging risk factors for cardiovascular disease and have been related to the whole spectrum of stroke, including transient ischemic attack, ischemic cerebral infarction and intracerebral haemorrhage. It has been shown that lacunar stroke or lacunar infarctions affecting the internal capsule or the protuberance are associated with a higher frequency of SDB. Acute stroke patients with associated SDB have a worse prognosis and a higher mortality as compared to patients with first-ever stroke without SDB. Preliminary studies provide evidence of the usefulness of treatment with continuous positive airway pressure when SDB is present in stroke patients.

Keywords: Apnea-hypopnea index; Cardiovascular risk factors; Continuous positive airway pressure; Ischemic stroke; Lacunar infarction; Sleep disordered.