Nickel-catalysed cyclopropanation of electron-deficient alkenes with diiodomethane and diethylzinc

Chem Commun (Camb). 2016 Feb 25;52(16):3372-5. doi: 10.1039/c5cc10296k.

Abstract

In the presence of a nickel catalyst, the cyclopropanation of electron-deficient alkenes with diiodomethane and diethylzinc is drastically accelerated. A wide range of cyclopropyl ketones, esters and amides can be accessed under these conditions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkenes / chemistry*
  • Catalysis
  • Cyclopropanes / chemistry*
  • Electrons
  • Hydrocarbons, Iodinated / chemistry*
  • Nickel / chemistry*
  • Organometallic Compounds / chemistry*

Substances

  • Alkenes
  • Cyclopropanes
  • Hydrocarbons, Iodinated
  • Organometallic Compounds
  • methylene iodide
  • Nickel
  • cyclopropane
  • diethylzinc