Clonal history of a cord blood donor cell leukemia with prenatal somatic JAK2 V617F mutation

P Hirsch; A C Mamez; R Belhocine; S Lapusan; R Tang; L Suner; D Bories; C Marzac; F Fava; O Legrand; M Mohty; L Douay; F Delhommeau

doi:10.1038/leu.2016.31

Clonal history of a cord blood donor cell leukemia with prenatal somatic JAK2 V617F mutation

Leukemia. 2016 Aug;30(8):1756-9. doi: 10.1038/leu.2016.31. Epub 2016 Mar 1.

Authors

P Hirsch^{1

2

3

4}, A C Mamez^{1

4}, R Belhocine⁴, S Lapusan^{3

4}, R Tang⁴, L Suner^{1

2

3

5}, D Bories⁶, C Marzac⁵, F Fava⁴, O Legrand^{1

2

3

4}, M Mohty^{1

2

3

4}, L Douay^{1

2

3

5}, F Delhommeau^{1

2

3

5}

Affiliations

¹ Sorbonne Universités, UPMC Univ Paris 06, UMR_S 938, CDR Saint-Antoine, Paris, France.
² INSERM, UMR_S 938, CDR Saint-Antoine, Paris, France.
³ Sorbonne Universités, UPMC Univ Paris 06, GRC n°7, Groupe de Recherche Clinique sur les Myéloproliférations Aiguës et Chroniques MYPAC, Paris, France.
⁴ AP-HP, Hôpital Saint-Antoine, Service d'Hématologie clinique et de thérapie cellulaire, Paris, France.
⁵ AP-HP, Hôpital Saint-Antoine & Hôpital Armand-Trousseau, Service d'hématologie biologique, Paris, France.
⁶ AP-HP, Hôpital Henri Mondor, Unité d'Hématologie Moléculaire, Créteil, France.

PMID: 26876594
DOI: 10.1038/leu.2016.31

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Allografts
Cord Blood Stem Cell Transplantation / adverse effects*
Humans
Janus Kinase 2 / genetics*
Leukemia, Myeloid, Acute / therapy*
Male
Middle Aged
Mutation
Neoplasms, Second Primary / genetics*
Tissue Donors

Substances

JAK2 protein, human
Janus Kinase 2