Statistical mechanics of neocortical interactions: Large-scale EEG influences on molecular processes

Abstract

Calculations further support the premise that large-scale synchronous firings of neurons may affect molecular processes. The context is scalp electroencephalography (EEG) during short-term memory (STM) tasks. The mechanism considered is Π=p+qA (SI units) coupling, where p is the momenta of free Ca(2+) waves, q the charge of Ca(2+) in units of the electron charge, and A the magnetic vector potential of current I from neuronal minicolumnar firings considered as wires, giving rise to EEG. Data has processed using multiple graphs to identify sections of data to which spline-Laplacian transformations are applied, to fit the statistical mechanics of neocortical interactions (SMNI) model to EEG data, sensitive to synaptic interactions subject to modification by Ca(2+) waves.

Keywords: Astrocytes; Neocortical dynamics; Short-term memory; Vector potential.