Crystal structure of N-(2-hy-droxy-5-methyl-phen-yl)benzamide

Rodolfo Moreno-Fuquen; Nory J Mariño; Alan R Kennedy

doi:10.1107/S2056989015020575

Crystal structure of N-(2-hy-droxy-5-methyl-phen-yl)benzamide

Acta Crystallogr E Crystallogr Commun. 2015 Nov 14;71(Pt 12):o943. doi: 10.1107/S2056989015020575. eCollection 2015 Dec 1.

Authors

Rodolfo Moreno-Fuquen¹, Nory J Mariño¹, Alan R Kennedy²

Affiliations

¹ Departamento de Química - Facultad de Ciencias Naturales y Exactas, Universidad del Valle, Apartado 25360, Santiago de Cali, Colombia.
² WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, 295 Cathedral Street, Glasgow G1 1XL, Scotland.

Abstract

In the title compound, C14H13NO2, the mean plane of the non-H atoms of the central amide fragment C-N-C(=O)-C (r.m.s. deviation = 0.029 Å) forms dihedral angles of 5.63 (6) and 10.20 (5)° with the phenyl and hy-droxy-phenyl rings, respectively. A short intra-molecular N-H⋯O contact is present. In the crystal, the mol-ecules are linked by O-H⋯O hydrogen bonds to generate C(7) chains along [100]. The chains are reinforced by weak C-H⋯O contacts, which together with the O-H⋯O bonds lead to R 2 (2)(7) loops. Very weak N-H⋯O inter-actions link the mol-ecules into inversion dimers.

Keywords: benzamide; benzanilide derivatives; biological activity; crystal structure.