Data on thrombotic ischemic lesions in the presence or absence of amyloid ß-protein precursor or its homolog amyloid precursor-like protein-2 in mice

Feng Xu; William E Van Nostrand

doi:10.1016/j.dib.2015.11.050

Data on thrombotic ischemic lesions in the presence or absence of amyloid ß-protein precursor or its homolog amyloid precursor-like protein-2 in mice

Data Brief. 2015 Dec 3:6:149-52. doi: 10.1016/j.dib.2015.11.050. eCollection 2016 Mar.

Authors

Feng Xu¹, William E Van Nostrand¹

Affiliation

¹ Departments of Neurosurgery and Medicine, Stony Brook University, Stony Brook, New York, USA.

Abstract

Amyloid ß-protein precursor (AßPP) and amyloid precursor-like protein-2 (APLP2) are potent inhibitors of thrombosis, see related article "The influence of the amyloid ß-protein and its precursor in modulating cerebral thrombosis" (Van Nostrand, 2016) [1]. Datapresented are images of photo-induced thrombotic ischemic stroke in wild-type mice, AßPP(-) (/) (-) mice and APLP2(-) (/) (-) mice, and the calculated infarct volume show approximately 40% and 33%, respectively, larger cerebral infarcts compared to wild-type mice.

Abstract

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