Current Role of Genetics in Hematologic Malignancies

Indian J Hematol Blood Transfus. 2016 Mar;32(1):18-31. doi: 10.1007/s12288-015-0584-4. Epub 2015 Sep 16.

Abstract

Rapidly changing field of genetic technology and its application in the management of hematological malignancies has brought significant improvement in treatment and outcome of these disorders. Today, genetics plays pivotal role in diagnosis and prognostication of most hematologic neoplasms. The utilization of genetic tests in deciding specific treatment of various hematologic malignancies as well as for evaluation of depth of treatment response is rapidly advancing. Therefore, it is imperative for practitioners working in the field of hemato-oncology to have sufficient understanding of the basic concepts of genetics in order to comprehend upcoming molecular research in this area and to translate the same for patient care.

Keywords: Genetics; Hematology; Molecular tests; Oncology.

Publication types

  • Review