Study of ideal topical pharyngeal anesthesia in upper gastrointestinal system endoscopy: A double-blind, randomized, controlled trial

Turk J Gastroenterol. 2016 Mar;27(2):103-7. doi: 10.5152/tjg.2015.150322. Epub 2016 Feb 5.

Abstract

Background/aims: This study is designed to determine which drug forms provide ideal pharyngeal anesthesia when used during upper gastrointestinal system endoscopy.

Materials and methods: A total of 180 patients were included in the study. Using the random number table, these patients were divided into three groups. Group 1, lidocaine gel+isotonic spray; Group 2, base lubricant gel+lidocaine spray; and Group 3: lidocaine gel+lidocaine spray. Data were collected from the patient identification form, compliance to operation form, and State Anxiety Inventory.

Results: Anesthetization and compliance to procedure scores were higher and anxiety scores were lower in Group 3 than in other groups (p<0.05). It was observed that as the compliance score increased, the anesthetization and satisfaction scores also increased; however, coughing during the procedure, duration of the procedure, and anxiety scores decreased (p<0.05). It was determined that as anesthetization scores increased, discomfort in the throat caused by the device, coughing during the procedure, and anxiety scores decreased (p<0.05).

Conclusion: Lidocaine gel and spray combination is the most ideal pharyngeal anesthesia to ensure the adaptation of the patient to the procedure and to decrease anxiety and discomfort during the procedure.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Anesthetics, Combined / administration & dosage*
  • Anesthetics, Local / administration & dosage*
  • Anxiety / epidemiology
  • Anxiety / etiology
  • Cough / epidemiology
  • Cough / etiology
  • Double-Blind Method
  • Endoscopy, Gastrointestinal / methods*
  • Endoscopy, Gastrointestinal / psychology
  • Female
  • Humans
  • Isotonic Solutions / administration & dosage*
  • Lidocaine / administration & dosage*
  • Male
  • Middle Aged
  • Operative Time
  • Patient Satisfaction
  • Pharynx / surgery

Substances

  • Anesthetics, Combined
  • Anesthetics, Local
  • Isotonic Solutions
  • Lidocaine