[Investigation of Prophylactic Efficacy of Triazavirin Against Experimental Forest- Spring Encephalitis on Albino Mice]

Antibiot Khimioter. 2015;60(5-6):8-11.
[Article in Russian]

Abstract

Prophylactic efficacy of Triazavirin against experimental Forest-Spring encephalitis was studied on albino mice. vs. the active drug Ribavirin. A significant increase of the animal lifespan in the test groups (from 4 to 5 days) and a statistically (p < or = 0.05) valid decrease of the virus accumulation level in the target organ (the brain) were observed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Azoles / pharmacology*
  • Brain / metabolism
  • Brain / pathology
  • Brain / virology
  • Cell Line
  • Disease Models, Animal
  • Encephalitis, Tick-Borne / metabolism
  • Encephalitis, Tick-Borne / pathology
  • Encephalitis, Tick-Borne / prevention & control*
  • Mice
  • Swine
  • Triazines / pharmacology*
  • Triazoles

Substances

  • Azoles
  • Triazines
  • Triazoles
  • riamilovir