Abstract
Prophylactic efficacy of Triazavirin against experimental Forest-Spring encephalitis was studied on albino mice. vs. the active drug Ribavirin. A significant increase of the animal lifespan in the test groups (from 4 to 5 days) and a statistically (p < or = 0.05) valid decrease of the virus accumulation level in the target organ (the brain) were observed.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Azoles / pharmacology*
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Brain / metabolism
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Brain / pathology
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Brain / virology
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Cell Line
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Disease Models, Animal
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Encephalitis, Tick-Borne / metabolism
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Encephalitis, Tick-Borne / pathology
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Encephalitis, Tick-Borne / prevention & control*
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Mice
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Swine
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Triazines / pharmacology*
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Triazoles
Substances
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Azoles
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Triazines
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Triazoles
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riamilovir