Molecular Pathology Informatics

Somak Roy

doi:10.1016/j.cll.2015.09.007

Molecular Pathology Informatics

Clin Lab Med. 2016 Mar;36(1):57-66. doi: 10.1016/j.cll.2015.09.007.

Author

Somak Roy¹

Affiliation

¹ Department of Pathology, Molecular and Genomic Pathology, University of Pittsburgh Medical Center, 3477 Euler way, Pittsburgh, PA 15213, USA. Electronic address: roys@upmc.edu.

PMID: 26851665
DOI: 10.1016/j.cll.2015.09.007

Abstract

Molecular informatics (MI) is an evolving discipline that will support the dynamic landscape of molecular pathology and personalized medicine. MI provides a fertile ground for development of clinical solutions to bridge the gap between clinical informatics and bioinformatics. Rapid adoption of next generation sequencing (NGS) in the clinical arena has triggered major endeavors in MI that are expected to bring a paradigm shift in the practice of pathology. This brief review presents a broad overview of various aspects of MI, particularly in the context of NGS based testing.

Keywords: Bioinformatics; Clinical informatics; Molecular informatics; Next-generation sequencing.

Publication types

Review