A Spontaneous Deletion of the US1.67/US2 Genomic Region on the Bovine Herpesvirus 1 Strain Cooper

F S Campos; W P Paim; A G Silva; R N Santos; R M Firpo; C M Scheffer; F Finoketti; A C Franco; P M Roehe

doi:10.1128/genomeA.01665-15

A Spontaneous Deletion of the US1.67/US2 Genomic Region on the Bovine Herpesvirus 1 Strain Cooper

Genome Announc. 2016 Feb 4;4(1):e01665-15. doi: 10.1128/genomeA.01665-15.

Authors

F S Campos¹, W P Paim¹, A G Silva¹, R N Santos¹, R M Firpo¹, C M Scheffer¹, F Finoketti¹, A C Franco¹, P M Roehe²

Affiliations

¹ Laboratório de Virologia, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
² Laboratório de Virologia, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil proehe@gmail.com.

Abstract

Bovine herpesvirus 1 (BoHV-1) is an alphaherpesvirus with a genome of 135 kb. Some BoHV-1 genes are nonessential and may be deleted from the viral genome. Here, a spontaneous gene deletion was identified in the BoHV-1 strain Cooper. Genes of the US1.67/US2 region were absent, as determined by next-generation sequencing.