Chromatographic separation of simulants of nerve and blister agents by combining one- and two-channel columns with different stationary phases

Huan Yuan; Xiaosong Du; Yi Li; Xulan Zhao; Ming Xu

doi:10.1002/jssc.201501138

Chromatographic separation of simulants of nerve and blister agents by combining one- and two-channel columns with different stationary phases

J Sep Sci. 2016 Apr;39(7):1295-9. doi: 10.1002/jssc.201501138.

Authors

Huan Yuan¹, Xiaosong Du¹, Yi Li¹, Xulan Zhao¹, Ming Xu²

Affiliations

¹ State Key Laboratory of Electronic Thin Films and Integrated Devices, University of Electronic Science and Technology of China, Chengdu, China.
² Key Laboratory of Information Materials of Sichuan Province, School of Electrical and Information Engineering, Southwest University for Nationalities, Chengdu, China.

PMID: 26843525
DOI: 10.1002/jssc.201501138

Abstract

A two-channel gas chromatography column and a single-channel column were made by deep reactive-ion etching technology. The two short columns were coated with different stationary phases, and then linked without a modulator. This is to aim at increasing the sample capacity and achieving a higher separation efficiency in complex environments. The results show that the capacity of the connected column is approximately 4 and 1.5 times larger than that of the single- and two-channel columns, respectively. The linked column was utilized to separate a six-component mixture, composed of three simulants of nerve and blister agents and three interfering vapors. The results demonstrate that the combined column has a remarkably higher separation efficiency than the individual columns, and an acceptable resolution is achieved although the total length of the linked column is only 1.5 m.

Keywords: Chemical warfare agents; Combined columns; Gas chromatography; Separation efficiency.

Publication types

Research Support, Non-U.S. Gov't