Laparoscopic cholecystectomy during pregnancy: A systematic review of 590 patients

Int J Surg. 2016 Mar:27:165-175. doi: 10.1016/j.ijsu.2016.01.070. Epub 2016 Jan 28.

Abstract

Background: The incidence of symptomatic biliary disease during pregnancy ranges from 0.05 to 8%. Cholecystectomy is one of the common operations performed during pregnancy and laparoscopic approach has gained popularity as an attractive alternative to open surgery.

Methods: In order to evaluate the safety, feasibility, outcomes and technical aspects of laparoscopic cholecystectomy during pregnancy a comprehensive search of Medline and Cohrane Library databases was conducted.

Results: Fifty-one studies were deemed eligible, in which laparoscopic cholecystectomy was attempted in 590 patients. The majority of the procedures (70.7%) were performed during the second trimester. Intraoperative and postoperative complications were observed in 3.5% and 4% of the study population. Conversion rate to open surgery was 2.2%. Fetal loss rate and preterm delivery rate were 0.4% and 5.7% respectively.

Conclusion: Laparoscopic cholecystectomy seems to be a safe alternative to open surgery during pregnancy.

Keywords: Cholecystectomy; Laparoscopy; Pregnancy.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Adult
  • Cholecystectomy, Laparoscopic*
  • Conversion to Open Surgery
  • Female
  • Gallbladder Diseases / surgery*
  • Humans
  • Pregnancy
  • Pregnancy Complications / surgery*