Localized topical steroid use and central serous retinopathy

J Dermatolog Treat. 2016 Oct;27(5):425-6. doi: 10.3109/09546634.2015.1136049. Epub 2016 Jan 29.

Abstract

Objectives: The link between topical steroid use and central serous retinopathy (CSR) is poorly understood as there are a limited number of reported cases, with most cases typically occurring in patients using oral or inhaled steroids. CSR is a common retinal disease that can cause loss of vision as a result of accumulated subretinal fluid leading to localized serous retinal detachments. CSR is associated with systemic steroid use. The objective of this case series and the review was to further understand the relationship between localized topical steroid use and CSR.

Methods: The medical charts of two patients who developed CSR after using topical steroids were reviewed.

Results: These cases demonstrate that CSR is associated with consistent topical steroid use to even limited areas of the body. These cases are unique, as other published cases describe patients who used topical steroids either on multiple or larger areas of the body.

Conclusion: It is critical that dermatologists are aware of this association, and refer patients who develop ocular symptoms after using topical steroids to ophthalmology.

Keywords: Central serous chorioretinopathy; drug-related side effects and adverse reactions; psoriasis; topical drug administration.

Publication types

  • Case Reports

MeSH terms

  • Administration, Topical
  • Central Serous Chorioretinopathy / chemically induced*
  • Female
  • Glucocorticoids / administration & dosage*
  • Glucocorticoids / adverse effects*
  • Humans
  • Middle Aged
  • Skin Diseases / drug therapy

Substances

  • Glucocorticoids