Cytomegalovirus infection in a cohort of pregnant women

S M El Sanousi; Z A Osman; A B S Mohmed; M S H Al Awfi

doi:10.1016/j.ajic.2015.11.002

Cytomegalovirus infection in a cohort of pregnant women

Am J Infect Control. 2016 Apr 1;44(4):e41-3. doi: 10.1016/j.ajic.2015.11.002. Epub 2016 Jan 22.

Authors

S M El Sanousi¹, Z A Osman², A B S Mohmed², M S H Al Awfi³

Affiliations

¹ Microbiology Department, Faculty of Veterinary, Khartoum University, Sudan.
² Microbiology Department, Faculty of Medical Laboratory Sciences, Omdurman Islamic University, Sudan.
³ Microbiology Department, Faculty of Medical Laboratory Sciences, Omdurman Islamic University, Sudan. Electronic address: mansooralawfi@gmail.com.

PMID: 26810886
DOI: 10.1016/j.ajic.2015.11.002

Abstract

Enzyme linked immunosorbent assay was used to detect the seroprevalence of cytomegalovirus (CMV) immunoglobulin M (IgM) and immunoglobulin G (IgG) in 300 pregnant women. Seventeen (5.7%) and 274 (91.3%) women were seropositive for IgM and IgG, respectively. There was significant increase in seroprevalence of CMV IgG and no significant increase in seroprevalence of CMV IgM among tested age groups. CMV IgM and IgG seroprevalence differed nonsignificantly by type of residence, the stage of pregnancy, and the level of education.

Keywords: ELISA; IgG; IgM; antibodies; congenital.

MeSH terms

Adolescent
Adult
Antibodies, Viral / blood*
Cohort Studies
Cytomegalovirus / immunology*
Cytomegalovirus Infections / epidemiology*
Enzyme-Linked Immunosorbent Assay
Female
Humans
Immunoglobulin G / blood
Immunoglobulin M / blood
Middle Aged
Pregnancy
Pregnancy Complications, Infectious / epidemiology*
Risk Factors
Seroepidemiologic Studies
Young Adult

Substances

Antibodies, Viral
Immunoglobulin G
Immunoglobulin M