Clinical neuroscience of amphetamine-type stimulants: From basic science to treatment development

Prog Brain Res. 2016:223:295-310. doi: 10.1016/bs.pbr.2015.07.010. Epub 2015 Oct 16.

Abstract

Abuse of amphetamine-type stimulants (ATS) poses a significant public health concern with known neurotoxic and neurocognitive effects to the user. In this chapter, we seek to integrate the latest research on ATS, particularly methamphetamine, by covering areas of pharmacology, neurocognitive effects, and the treatment of ATS use disorders with the goal of advancing the clinical neuroscience of ATS and highlighting avenues for future research.

Keywords: ATS use disorders; Addiction; Amphetamine; Clinical neuroscience; Methamphetamine; Stimulants; Treatment.

Publication types

  • Review

MeSH terms

  • Amphetamine / pharmacology*
  • Amphetamine-Related Disorders / drug therapy*
  • Amphetamine-Related Disorders / physiopathology
  • Animals
  • Central Nervous System Stimulants / pharmacology*
  • Humans
  • Neurosciences
  • Neurotoxicity Syndromes / drug therapy*
  • Neurotoxicity Syndromes / physiopathology
  • Research*

Substances

  • Central Nervous System Stimulants
  • Amphetamine